Week #6
*denotes home team
| PRO FOOTBALL - THURSDAY, OCTOBER 13, 2022 | |||
| 1 COMMANDERS | 5:15 PM | 2 BEARS* | PK |
| PRO FOOTBALL - SUNDAY, OCTOBER 16, 2022 | |||
| 3 BUCCANEERS | 10:00 AM | 4 STEELERS* | +8 |
| 5 BENGALS | 10:00 AM | 6 SAINTS* | +2 |
| 7 COLTS* | 10:00 AM | 8 JAGUARS | +1.5 |
| 9 BROWNS* | 10:00 AM | 10 PATRIOTS | +2.5 |
| 11 PACKERS* | 10:00 AM | 12 JETS | +7 |
| 13 RAVENS | 10:00 AM | 14 GIANTS* | +5.5 |
| 15 VIKINGS | 10:00 AM | 16 DOLPHINS* | +3.5 |
| 17 49ERS | 10:00 AM | 18 FALCONS* | +5.5 |
| 19 RAMS* | 1:05 PM | 20 PANTHERS | +10.5 |
| 21 CARDINALS | 1:05 PM | 22 SEAHAWKS* | +2.5 |
| 23 BILLS | 1:25 PM | 24 CHIEFS* | +2.5 |
| 25 EAGLES* | 5:20 PM | 26 COWBOYS | +6 |
| PRO FOOTBALL - MONDAY, OCTOBER 17, 2022 | |||
| 27 CHARGERS* | 5:15 PM | 28 BRONCOS | +5 |
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